Studies involving humans are for the most part badly designed. A few quality studies have been carried out over the years, starting in 1998 with a double-blind, placebo-controlled trial of 135 adults over 12 weeks published in The Journal of the American Medical Association. They found no evidence that hydroxycitric acid, the active ingredient in weight loss products made from garcinia cambogia, produced significant weight loss.
The American Journal of Clinical Nutrition in 2004 published a systematic review of meta-analyses and clinical trials on dietary supplements for weight loss by complementary medicine researchers at the Universities of Exeter and Plymouth. None of the over-the-counter weight loss aids worked, including garcinia cambogia.
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The four primary approaches to the study of geography are spatial analysis, area studies, the man-land relationship, and earth science. While most of the physical world today has been explored and charted, much remains to be mapped in the human world, and this is the goal of geographers at most major universities today.
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